| D20 Modern | 2002 | Wizards of the Coast | United States |
| D20 System | 2000 | Wizards of the Coast | United States |
| D6 Adventure | 2004 | West End Games | United States |
| D6 Fantasy | 2004 | West End Games | United States |
| D6 Space | 2004 | West End Games | United States |
| D6 System | 1996 | West End Games | United States |
| Daggerheart | 20 May 2025 | Darrington Press | United States |
| Dallas: The Television Role-Playing Game | 1980 | Simulations Publications, Inc. | United States |
| Danger International | 1985 | Hero Games | United States |
| Dangerous Journeys | 1992 | Game Designers' Workshop | United States |
| Daredevils | 1982 | Fantasy Games Unlimited | United States |
| Dark Ages: Vampire | 2002 | White Wolf Publishing | United States |
| Dark Champions | 1993 | Hero Games | United States |
| Dark Conspiracy | 1991 | Game Designers' Workshop | United States |
| Dark Dungeons | 2010 | — | — |
| Dark Earth | 1997 | Multisim | France |
| Dark Heresy (1st edition) | 2008 | — | United States |
| Dark Heresy (2nd edition) | 2014 | — | — |
| Dark Realms | 1997 | — | — |
| Dark Streets | 2012 | — | — |
| Darkpages | 2008 | Memento Mori Theatricks | United States |
| Darwin's World | 2001 | — | — |
| Dawning Star | 2005 | Blue Devil Games | United States |
| DC Adventures: Heroes & Villains | 2010 | — | — |
| DC Heroes | 1985 | Mayfair Games | United States |
| DC Universe Roleplaying Game | 1999 | West End Games | United States |
| De Profundis | 2001 | — | — |
| Dead Inside | 2003 | Atomic Sock Monkey Press | United States |
| Dead Reign | 2008 | Palladium Books | United States |
| Deadlands | 1996 | Pinnacle Entertainment Group | United States |
| Deadlands: Hell on Earth | 1998 | Pinnacle Entertainment Group | United States |
| Deadlands: Lost Colony | 2002 | Pinnacle Entertainment Group | United States |
| Deadlands: Reloaded | 2005 | Pinnacle Entertainment Group | United States |
| Deathwatch | 2010 | — | United States |
| Degenesis | May 2004 | — | — |
| Degenesis | 2004 | Sixmorevodka | Germany |
| Degenesis Rebirth | November 2016 | Edge Studio | — |
| Delta Force: America Strikes Back! | 1986 | — | — |
| Delving Deeper | 2012 | — | — |
| Demon City Shinjuku Role-Playing Game | 1999 | — | — |
| Demon Hunters Role Playing Game | 2008 | Margaret Weis Productions | United States |
| Demon: The Fallen | 2002 | White Wolf Publishing | United States |
| Deryni Adventure Game | 2005 | — | — |
| Desafio dos Bandeirantes | 1992 | — | Brazil |
| Devâstra | 2009 | — | France |
| Diana: Warrior Princess | 2003 | — | — |
| Diaspora | 2009 | Evil Hat Productions | United States |
| DIE RPG | 2022 | — | — |
| Dinky Dungeons | 1985 | — | — |
| Dinosaur Planet: Broncosaurus Rex | 2001 | — | — |
| Dirty Secrets | 2007 | Black and Green Games | United States |
| Disaster Strikes! | 2013 | Black Armada Games | United Kingdom |
| DK system | 2006 | Éditions John Doe / Chibi | France |
| Do: Pilgrims of the Flying Temple | 2011 | Evil Hat Productions | United States |
| Doctor Who Roleplaying Game | 2009 | Cubicle 7 | United Kingdom |
| Dodécaèdre | 2014 | self-published work | France |
| Dog Eat Dog | 2012 | — | Philippines |
| Dogs in the Vineyard | 2004 | Lumpley Games | United States |
| Domination | 1989 | — | — |
| Dominion Rules | 1999 | — | — |
| Don't Look Back | 1994 | — | — |
| Don't Rest Your Head | 2006 | Evil Hat Productions | United States |
| Donjon | 2002 | CRN Games | United States |
| Donjon & Cie | 2022 | Black Book Éditions | — |
| Dracurouge | 2017 | — | Japan |
| Dragepust | 2024 | Outland forlag, Spillforlaget | Norway |
| Dragon Age | 2010 | Green Ronin Publishing | United States |
| Dragon Ball Z: The Anime Adventure Game | 1999 | R. Talsorian Games | United States |
| Dragon de poche | 2013 | Éditions John Doe / Chibi | France |
| Dragon Lords of Melniboné | 2001 | Chaosium | United States |
| Dragon Storm | 1996 | — | — |
| Dragon Warriors | 1985 | — | — |
| Dragonlance: Fifth Age | 1996 | TSR | United States |
| DragonQuest | 1980 | Simulations Publications, Inc. | United States |
| DragonRaid | 1984 | — | United States |
| Dragonroar | 1985 | — | — |
| Dragonstar | 2001 | — | United States |
| Drakar och Demoner | 1982 | RiotMinds, Free League Publishing, Neogames, Target Games | Sweden |
| DramaSystem | 2012 | — | — |
| Draug | 2004 | — | Norway |
| Dračí doupě | 1990 | — | Czech Republic |
| Dread | 2005 | — | — |
| Dread: The First Book of Pandemonium | 2009 | — | — |
| Dream Askew | 2014 | Buried Without Ceremony | United States |
| Dream Park: The Roleplaying Game | 1992 | R. Talsorian Games | United States |
| Dreaming Cities | 2005 | Guardians of Order | Canada |
| Drizzit - Il gioco di ruolo | — | — | Italy |
| Droids | 1983 | — | — |
| Druid | 1993 | Editrice Giochi | Italy |
| Dune: Adventures in the Imperium | 2021 | Modiphius Entertainment | — |
| Dune: Chronicles of the Imperium | 2000 | — | France |
| Dungeon Crawl Classics | 2012 | Goodman Games | United States |
| Dungeon Master Option: High-Level Campaigns | 1995 | TSR | United States |
| Dungeon Master's Guide 2 | 2009 | — | United States |
| Dungeon Master's Guide II | June 2005 | Wizards of the Coast | United States |
| Dungeon Squad! | 2005 | self-published work | — |
| Dungeon World | 2012 | Sage Kobold Productions | United States |
| Dungeonesque | 2017 | — | — |
| Dungeons & Dragons | 1974 | Wizards of the Coast | United States |
| Dungeons & Dragons (3.5 edition) | July 2003 | Wizards of the Coast | United States |
| Dungeons & Dragons (3rd edition) | 2000 | Wizards of the Coast | United States |
| Dungeons & Dragons (4th basic edition) | 1991 | TSR | United States |
| Dungeons & Dragons (4th edition) | 2008 | Wizards of the Coast | United States |
| Dungeons & Dragons (5th edition) | 2014 | Wizards of the Coast | United States |
| Dungeons & Dragons (basic edition) | 1977 | TSR | United States |
| Dungeons & Dragons (original edition) | 1974 | TSR | United States |
| Dungeons & Dragons (original edition, 1st print) | 1974 | TSR | United States |
| Dungeons & Dragons (original edition, 4th print) | 1975 | TSR | United States |
| Dungeons & Dragons Basic Set, Holmes version | 1977 | TSR | United States |
| Dungeons & Dragons Basic Set, Mentzer version | 1983 | TSR | United States |
| Dungeons & Dragons Basic Set, Moldvay version | 1981 | TSR | United States |
| Dungeons & Dragons Companion Set | 1984 | TSR | United States |
| Dungeons & Dragons Expert Set, Cook version | 1981 | TSR | United States |
| Dungeons & Dragons Expert Set, Mentzer version | 1983 | TSR | United States |
| Dungeons & Dragons Game | 1991 | TSR | United States |
| Dungeons & Dragons Immortals Rules | 1986 | TSR | United States |
| Dungeons & Dragons Master Rules | 1985 | TSR | United States |
| Dungeons & Dragons Next | 2012 | Wizards of the Coast | United States |
| Dungeonslayers | 2009 | — | Germany |
| Durance | 2012 | — | — |
| Dust Devils | 2002 | — | United States |
| Dzikie Pola | 1997 | Wydawnictwo MAG | Poland |
| Démiurges | 2017 | — | France |