| F.A.T.A.L. | 2004 | — | United States |
| Fading Suns | 1996 | Holistic Design | United States |
| Faery's Tale | 2006 | — | — |
| Fall of Delta Green | 2018 | Pelgrane Press | United States |
| Fanhunter, el juego de rol épicodecadente | 1992 | — | Spain |
| Fanpiro | 2001 | — | Spain |
| Fantasy AGE | 2015 | Green Ronin Publishing | United States |
| Fantasy Hero | 1985 | Hero Games | United States |
| Fantasy Wargaming | 1981 | — | United Kingdom |
| Farscape | 2002 | Alderac Entertainment Group | United States |
| Fastlane | 2004 | — | — |
| Fate | 2003 | Evil Hat Productions | United States |
| Fate Accelerated | 2013 | Evil Hat Productions | United States |
| Fate of the Norns | 1993 | — | Canada |
| Fear Itself | 2007 | Pelgrane Press | United States |
| Fear Itself 1st edition | 2006 | Pelgrane Press | United States |
| Fear Itself 2nd edition | 2016 | Pelgrane Press | United States |
| Fellowship: A Tabletop Adventure Game | 2015 | — | — |
| Feng Shui | 1996 | Daedalus Entertainment, Atlas Games | United States |
| FHTAGN | 2017 | — | — |
| Fiasco | 2018 | Bully Pulpit Games | United States |
| Field Guide to Encounters | 1982 | Judges Guild | United States |
| Fifth Cycle | 1990 | — | — |
| Final Frontier | 2006 | — | — |
| Fireborn | 2004 | — | United States |
| Firefly Role-Playing Game | 2014 | Margaret Weis Productions | United States |
| Five Torches Deep | 2019 | self-published work | — |
| Flash Gordon & the Warriors of Mongo | 1977 | Fantasy Games Unlimited | United States |
| Flashing Blades | 1984 | Fantasy Games Unlimited | United States |
| For Gold & Glory | 2012 | — | — |
| For the Queen | 2019 | Darrington Press, Evil Hat Productions | Canada |
| Forbidden Kingdoms | 2001 | — | — |
| Forbidden Lands | 2018 | — | — |
| Forgotten Chronicles | 2009 | Black Book Éditions | France |
| Forgotten Futures | 1993 | — | — |
| Four Against Darkness | — | System Matters | Italy |
| Freaks' Squeele | 2017 | 2d Sans Faces | Switzerland |
| Freedom Fighters | 1986 | — | — |
| Freemarket | 2009 | — | — |
| Fringeworthy | 1982 | Tri Tac Games | United States |
| FTL:2448 | 1982 | Tri Tac Games | United States |
| FU: The Freeform/Universal RPG | 2010 | — | — |
| Fudge | 1992 | Grey Ghost Press | United States |
| Furry Pirates | 1999 | — | — |
| Fusion | 2000 | Høst & Søn | — |
| Future Worlds | 1987 | — | — |
| Fuzion | 1998 | Hero Games | United States |
| Fvlminata | 2001 | — | — |